340B Drug Pricing Program Database

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The Q2 2025 registration window for covered entities is open from 4/1/2025 - 4/15/2025.

340B Office of Pharmacy Affairs Information System Participant Site

Welcome to 340B OPAIS - Create New User
Do not create an OPAIS account unless you are requesting to be an AO or PC for a covered entity or manufacturer (or are an ADR point of contact).All other OPAIS users should use the public user interface for OPAIS at https://340bopais.hrsa.gov/